Isobel McCreath married William Watson at at St. Quivox on 4 September 1814. They had six children:
David Watson born 5 january 1814, born Newton on Ayr. Died 4 June 1849. Kilwinning.
John Watson born 20 June 1819, born Newton on Ayr. Died 20 June 1875, Newton Ayr.
Ann Watson born 1822
Agnes Watson born 1824. Died 20 June 1895, Newton on Ayr.
Robert Watson born 1826. Died 26 June 1883, Ayr.
Thomas Watson born 1878. Died 2 March 1878, Mount Oliphant Farm, Ayr